Gradient Biotech
U

Menu

Research Areas

Computational BiologySingle-cell, bulk RNA-seq, spatial, and biomarkers
CardiologyCardiovascular signals, cohorts, and interpretationImmunologyImmune cell states, signaling networks, and repertoire dynamicsNeurologyBrain connectivity, functional imaging, and electrophysiologyOncologyTumor microenvironment, immune response, mutations, and survivalPathologyWhole-slide imaging, tissue quantification, and spatial pathology

Application

Documentation

Documentation

Back to studies

Overview

Immunology workflows support immune state discovery, repertoire diversity, cytokine signaling, disease cohort comparison, and multi-modal immune profiling.

Use case index

Use caseResearch questionKey capabilities
Immune atlas and annotationWhich immune populations and states are present?Annotation, state scoring, composition
Repertoire diversityWhich clones are expanded or shared across samples?TCR/BCR clonotypes, diversity, overlap
Cytokine signalingWhich ligand-receptor and cytokine pathways dominate?Communication, cytokine networks, pathway deltas
Disease cohort comparisonHow do immune profiles vary across disease contexts?Cohort metadata, composition, trajectory, spatial patterns
Multi-modal profilingHow do protein, ATAC, and cytometry measurements support immune phenotypes?CITE-seq, ATAC, multiome, cytometry

Common starting data

  • per-cell annotations
  • scRNA-seq or CITE-seq tables
  • VDJ contig/AIRR/bulk repertoire tables
  • spatial cell coordinate tables
  • cohort metadata
  • ATAC peak tables
  • cytometry event tables

Research-only scope

These use cases support exploratory and translational research. They are not clinical diagnostic workflows.